Tag: "Fabry-Disease"

Generation of -Knockout Human Embryonic Stem Cell Lines to Model Autophagic Dysfunction and Exosome Secretion in Fabry Disease-Associated Hypertrophic Cardiomyopathy.

Cells

Monday 08 April 2019
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metabolismhumansanimalsgeneticsexosomescytologymiceinduced pluripotent stem cellsphysiologydrug effectscell lineembryonic stem cellscell differentiationpathologyfemaleculturedcellscell proliferationmalemicrornasgene expression regulationmethodschemistrymesenchymal stem cellscell movementfibroblastsimmunologyratstumoranimaltransplantationbiomarkersdisease modelspharmacologytherapycell communicationinbred c57blmyocytescardiacextracellular vesiclesneuronsapoptosisbloodculture mediarnaconditionedembryoadministration dosagehuman embryonic stem cellsmyocardiumneoplasmsagedbraincell survivalcellular reprogrammingdeficiencydnabinding proteinsmammalianmelanomamicroscopymodelsneural stem cellssignal transductionstem cell transplantationbiologicalcellular senescenceendothelial cellsmutationpluripotent stem cellsregenerationadultalzheimer diseasecell culture techniquescytokinesdevelopmentaldrug delivery systemsenzymologyfibrosisgenetichek293 cellsimmunohistochemistrymouse embryonic stem cellsmuscleregenerative medicineastrocytesbioengineeringbiosynthesisblottingcell and tissuebased therapycellderived microparticlescoculture techniquesdownregulationepigenesisetiologyhearthuman umbilical vein endothelial cellslungmyocardial infarctionneoplasticneovascularization